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This Brief summarizes the current research on the novel BRICHOS domain, which is a chaperone domain found in a variety of proteins and is shown to exhibit anti-amyloidogenic chaperone-like functions. The BRICHOS domain is defined from sequence similarities, lacks established physiological function(s) and is found about 10 distantly related pro-protein families, several of which are associated with human disease. In this work, the authors review the mechanism by which BRICHOS inhibits Ass aggrega...Vis mer
Om boken
ISBN
9783319165639
Forlag
Springer International Publishing AG
Publiseringsår
2015
Språk
Utgave
1
Originaltittel
The BRICHOS Domain
Format
Frakt og retur
Frakt
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