For a comprehensive understanding of human physiology - from molecules to systems -turn to the latest edition of Medical Physiology. This updated textbook is known for its unparalleled depth of information, equipping students with a solid foundation for a future in medicine and healthcare, and providing clinical and research professionals with a reliable go-to reference. Complex concepts are presented in a clear, concise, and logically organized format to further facilitate understanding and retention.Clear, didactic illustrations visually present processes in a clear, concise manner that is easy to understand.Intuitive organization and consistent writing style facilitates navigation and comprehension.Takes a strong molecular and cellular approach that relates these concepts to human physiology and disease.Student Consult eBook version included with purchase. This enhanced eBook experience includes access -- on a variety of devices -- to the complete text with thorough hyperlinking, images, 10 animations, and copious linkout notes prepared by the Editors.An increased number of clinical correlations provides a better understanding of the practical applications of physiology in medicine.Highlights new breakthroughs in molecular and cellular processes, such as the role of epigenetics, necroptosis, and ion channels in physiologic processes, to give insights into human development, growth, and disease.Several new authors offer fresh perspectives in many key sections of the text, and meticulous editing makes this multi-authored resource read with one unified voice. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should online access to the web site be discontinued.

Nyeste versjon av den beste fysiologiboka jeg har brukt. For a comprehensive understanding of human physiology - from molecules to systems -turn to the latest edition of Medical Physiology.

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For a comprehensive understanding of human physiology - from molecules to systems -turn to the latest edition of Medical Physiology. This updated textbook is known for its unparalleled depth of information, equipping students with a solid foundation for a future in medicine and healthcare, and providing clinical and research professionals with a reliable go-to reference. Complex concepts are presented in a clear, concise, and logically organized format to further facilitate understanding and retention.

On the Road by Jack Kerouac is the exhilarating novel that defined the Beat Generation and is a 2012 major motion picture starring Kristen Stewart, Kirsten Dunst and Sam Riley, beautifully repackaged as part of the Penguin Essentials range.'What's your road, man? - holyboy road, madman road, rainbow road, guppy road, any road. It's an anywhere road for anybody anyhow.'Sal Paradise, young and innocent, joins the slightly crazed Dean Moriarty on a breathless, exuberant ride back and forth across the United States. Their hedonistic search for release or fulfilment through drink, sex, drugs and jazz becomes an exploration of personal freedom, a test of the limits of the American Dream.A brilliant blend of fiction and autobiography, Jack Kerouac's exhilarating novel defined the new 'Beat' generation and became the bible of the counter culture.'On the Road sold a trillion Levis and a million espresso machines, and also sent countless kids on the road. The alienation, the restlessness, the dissatisfaction were already there waiting when Kerouac pointed out the road' William Burroughs'Pop writing at its best. It changed the way I saw the world, making me yearn for fresh experience' Hanif Kureishi, Independent on Sunday Jack Kerouac was born in Lowell, Massachusetts, in 1922. Educated by Jesuit brothers in Lowell, he decided to become a writer at age seventeen and developed his own writing style, which he called 'spontaneous prose'. He used this technique to record the life of the American 'traveler' and the experiences of the Beat Generation, most memorably in On the Road and also in The Subterraneans and The Dharma Bums. His other works include Big Sur, Desolation Angels, Lonesome Traveler, Visions of Gerard, Tristessa, and a book of poetry called Mexico City Blues. Jack Kerouac died in 1969.

Kansas City has a rich heritage of residential architecture that speaks to the importance of this Midwestern metropolis during its boom years between 1880 and 1930. The forty houses covered here were erected by the city's leading plutocrats, such as newspaper publisher William Rockhill Nelson, whose fortune helped establish the Nelson-Atkins Museum; minerals magnate August R. Meyer; lumber baron Robert A. Long; oilman Ernest C. Winters; and Walter E. Bixby of Kansas City Life Insurance. Among the noted architects profiled are Edward W. Tanner; Henry F. Hoit; Louis S. Curtiss; the New York firm of George Brown Post in collaboration with Kansas City based architect Roger Gilman (Dean of RISD, 1919-1929); and Mary Rockwell Hook (one of the first women to study at the Ecole des Beaux Arts in Paris). Most of these houses were designed in the European and American revival styles prevalent during this period, although distinguished by a unique Midwestern sensibility.

The largest rebellion in the history of Spain's American empire--a conflict greater in territory and costlier in lives than the contemporaneous American Revolution--began as a local revolt against colonial authorities in 1780. As an official collector of tribute for the imperial crown, Jos Gabriel Condorcanqui had seen firsthand what oppressive Spanish rule meant for Peru's Indian population. Adopting the Inca royal name Tupac Amaru, he set events in motion that would transform him into Latin America's most iconic revolutionary figure.Tupac Amaru's political aims were modest at first. He claimed to act on the Spanish king's behalf, expelling corrupt Spaniards and abolishing onerous taxes. But the rebellion became increasingly bloody as it spread throughout Peru and into parts of modern-day Bolivia, Chile, and Argentina. By late 1780, Tupac Amaru, his wife Micaela Bastidas, and their followers had defeated the Spanish in numerous battles and gained control over a vast territory. As the rebellion swept through Indian villages to gain recruits and overthrow the Spanish corregidors, rumors spread that the Incas had returned to reclaim their kingdom.Charles Walker immerses readers in the rebellion's guerrilla campaigns, propaganda war, and brutal acts of retribution. He highlights the importance of Bastidas--the key strategist--and reassesses the role of the Catholic Church in the uprising's demise. The Tupac Amaru Rebellion examines why a revolt that began as a multiclass alliance against European-born usurpers degenerated into a vicious caste war--and left a legacy that continues to influence South American politics today.

to arrive at some temporary consensus model or models; and to present reliable physical data pertaining to water under a range of conditions, i.e., "Dorsey revisited," albeit on a less ambitious scale. I should like to acknowledge a debt of gratitude to several of my col- leagues, to Prof. D. J. G. Ives and Prof. Robert L. Kay for valuable guidance and active encouragement, to the contributors to this volume for their willing cooperation, and to my wife and daughters for the understanding shown to a husband and father who hid in his study for many an evening. My very special thanks go to Mrs. Joyce Johnson, who did all the cor- respondence and much of the arduous editorial work with her usual cheerful efficiency. F. FRANKS Biophysics Division Unilever Research Laboratory ColworthjWelwyn Colworth House, Sharnbrook, Bedford March 1972 Contents Chapter 1 Introduction-Water, the Unique Chemical F. Franks I. lntroduction ...2. The Occurrence and Distribution of Water on the Earth 2 3. Water and Life ...4 4. The Scientific Study of Water-A Short History ...8 5. The Place of Water among Liquids ...13 ...Chapter 2 The Water Moleeule C. W. Kern and M. Karplus 1. Introduction...21 ...2.Principles of Structure and Spectra: The Born-Oppenheimer Separation ...22 ...3. The Electronic Motion ...26 3.1. The Ground Electronic State of Water ...31 3.2. The Excited Electronic States of Water ...50 4. The Nuclear Motion ...52 5. External-Field Effects ...70 5.1. Perturbed Hartree-Fock Method ...74 ...

One of America's most significant architects of conservation and the environment, Stewart Udall, comes to life in this environmental biography. Perhaps no other public official or secretary of the interior has ever had as much success in environmental protection, natural resource conservation, and outdoor recreation opportunity creation as Udall. A progressive Mormon, born and raised in rural Arizona, Udall served as the U.S. Secretary of the Interior under the presidential cabinets of John F. Kennedy and Lyndon Baines Johnson from 1961-1969. During these eight years, he established dozens of new national park units and national wildlife refuges, wrote the Endangered Species Preservation Act, lobbied for unpolluted water, and offered ways to beautify urban spaces and bring the impoverished out of poverty. Later in life, he continued as an advocate for conservation and the environment, specifically by proposing solutions to the challenges associated with global warming and the widespread use of oil.What can we learn from this farsighted individual?In a day and age of partisan politics, poor congressional approval ratings, and global warming and climate change, this captivating biography offers a profound and historical record into Udall's life-long devotion to environmental issues he cared about most deeply-issues more relevant today than they were then. Intimate moments include Udall's learning of the Kennedy assassination, his push for civil rights for African Americans, his meeting in the U.S.S.R. with Nikita Khrushchev-the first Kennedy cabinet member to do so-and his warnings about global warming 50 years prior to Al Gore's Nobel Prize-winning film.

Winner of the PEN Center USA Literary Award for Research NonfictionNamed one of the Top 3 JFK Books by Parade Magazine. Named 1 of The 5 Essential Kennedy assassination books ever written by The Daily Beast. Named one of the Top Nonfiction Books of 2013 by Kirkus Reviews. In the months and weeks before the fateful November 22nd, 1963, Dallas was brewing with political passions, a city crammed with larger-than-life characters dead-set against the Kennedy presidency. These included rabid warriors like defrocked military general Edwin A. Walker; the world's richest oil baron, H. L. Hunt; the leader of the largest Baptist congregation in the world, W.A. Criswell; and the media mogul Ted Dealey, who raucously confronted JFK and whose family name adorns the plaza where the president was murdered. On the same stage was a compelling cast of marauding gangsters, swashbuckling politicos, unsung civil rights heroes, and a stylish millionaire anxious to save his doomed city. Bill Minutaglio and Steven L. Davis ingeniously explore the swirling forces that led many people to warn President Kennedy to avoid Dallas on his fateful trip to Texas. Breathtakingly paced, DALLAS 1963 presents a clear, cinematic, and revelatory look at the shocking tragedy that transformed America. Countless authors have attempted to explain the assassination, but no one has ever bothered to explain Dallas-until now. With spellbinding storytelling, Minutaglio and Davis lead us through intimate glimpses of the Kennedy family and the machinations of the Kennedy White House, to the obsessed men in Dallas who concocted the climate of hatred that led many to blame the city for the president's death. Here at long last is an accurate understanding of what happened in the weeks and months leading to John F. Kennedy's assassination. DALLAS 1963 is not only a fresh look at a momentous national tragedy but a sobering reminder of how radical, polarizing ideologies can poison a city-and a nation.

This book focuses on the emerging and expanding areas of research on ASD and their potential to lead to better diagnosis and more effective therapies. These areas include innovative and integrative approaches to genetic/genomic analyses and investigations of epigenetic contributions, including the role of noncoding RNAs, DNA methylation, alternative splicing, RNA editing, and faulty translation in gene regulation and expression, metabolic and immune dysfunction, co-morbidities, as well as hormonal and gene-environment interactions that may increase risk for ASD.Within each chapter, experts review cutting-edge research as well as provide their perspective on the future of research in their respective areas, including the challenges involved and the types of studies or advances that are necessary to move the field forward to achieve predicted translational goals.Contributors: Argel Aguilar-Valles, Evdokia Anagnostou, Emma Ashwin, Bonnie Auyeung, Kelly M Bakulski, Simon Baron-Cohen, Margaret L Bauman, Donna Betts, Chad A Bousman, Daniel B Campbell, Manuel F Casanova, Bhismadev Chakrabarti, Gursharan Chana, Abha Chauhan, Ved Chauhan, Jessica DeWitt, Keith W Dunaway, Alal Eran, Ian P Everall, M Daniele Fallin, Richard E Frye, Piers Gillett, Matthew Ginsberg, Christos G Gkogkas, Rhonda J Greenhaw, Simon G Gregory, Elena L Grigorenko, Feng Gu, Rebecca Harmer, Martha Herbert, Valerie W Hu, Karen L Jones, Petra Kern, Arkady Khoutorsky, Rebecca Knickmeyer, Isaac S Kohane, Louis M Kunkel, Janine M LaSalle, Michael V Lombardo, Deepali Mankad, Marvin Natowicz, Laura Nicholls, Christos Pantelis, Natalia Rakhlin, Radhika Ramadas, Daniel A Rossignol, Tewarit Sarachana, Stephen W Scherer, Gabriela Schmulevich, Ayten Shah, Frank R Sharp, Alison B Singer, Efstratios Skafidas, Estate M Sokhadze, Nahum Sonenberg, Boryana Stamova, Zohreh Talebizadeh, Renee Testa, Judy Van de Water, Irina Voineagu, Daniel Williams, Ryan K C Yuen, Daniela Zantomio.

Die -Geschichte der amerikanischen Literatur- von Walter F. Schirmer, die zuerst 1937 veroffentlicht wurde und 1954 in einer durch den Einschluss des amerikanischen Schrifttums erweiterten Umarbeitung erschien, liegt hier in einer Neuauflage aus dem Jahr 1983 vor. Diese Neubearbeitung wurde einem Kreis von Schulern und Freunden Schirmers ubertragen, die die verschiedenen Epochen einer durchgreifenden Revision unterzogen und Text und Anmerkungen der vorausgehenden funften Auflage durch Erweiterungen, Kurzungen und Neufassungen aktualisiert haben. Band II behandelt die Literatur des Klassizismus, der Romantik, der viktorianischen Zeit sowie des 20. Jahrhunderts."

An examination of the potential and limitations of deliberative consensus as a way to achieve effective international environmental governance.In this book, Walter Baber and Robert Bartlett explore the practical and conceptual implications of a new approach to international environmental governance. Their proposed approach, juristic democracy, emphasizes the role of the citizen rather than the nation-state as the source of legitimacy in international environmental law; it is rooted in local knowledge and grounded in democratic deliberation and consensus. The aim is to construct a global jurisprudence based on collective will formation. Building on concepts presented in their previous book, the award-winning Global Democracy and Sustainable Jurisprudence, Baber and Bartlett examine in detail the challenges that consensus poses for a system of juristic democracy. Baber and Bartlett analyze the implications of deliberative consensus for rule-bounded behavior, for the accomplishment of basic governance tasks, and for diversity in a politically divided and culturally plural world. They assess social science findings about the potential of small-group citizen panels to contribute to rationalized consensus, drawing on the extensive research conducted on the use of juries in courts of law. Finally, they analyze the place of juristic democracy in a future "consensually federal" system for earth system governance.

What was it like to live through the only war America lost in the twentieth century? Firebase Tan Tru answers that question by describing one man's adventures fighting in Vietnam's Mekong Delta during the peak of the war in 1969. A unique feature of this story is that it focuses upon that rare enlisted man who was already a college graduate, struggling to cope not only with the authoritarian rigidity of America's Army but also the horror and madness of the war itself. It describes both harrowing nearly fatal clashes in combat and the numerous surreal experiences encountered in that foreign land. If you are curious about how a bizarre war like Vietnam changes a thoughtful young man into cynicism and skepticism, then Firebase Tan Tru is a book you need to read. It provides insights into the personal psychology of both America's Vietnam era officers and the enlisted men they lead as well as our Vietnamese allies and our Vietnamese enemies.

A cellular and molecular approach to physiology... in a clear, easy to understand style!

Uses original essays, cases, and materials to study the very enterprise by which a constitution is interpreted and a constitutional government created. The book explores the American polity as both a constitutional and democratic entity.