This new, updated edition of New Clinical Genetics continues to offerthe most innovative case-based approach to modern genetics. It is usedworldwide as a textbook for medical students, and is also an essential guide for genetic counselors and clinical and nursegeneticists.

Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation. Key features:Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biologyAccessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanismsSummary boxes at the end of each chapter provide clear learning pointsAnnotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further studyReorganized into five sections for improved access to related topicsAlso new to this edition - brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary GeneticsA proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the `go-to' book for those studying human molecular genetics or genomics courses around the world.

The fast-track MBA in communicationImagine having instant access to the world's smartest thinking on human communication - and being shown exactly what to do to guarantee that all of your communication is right, every time. Communication Genius makes it easy to apply the scientific facts that researchers know about communication to the real world. 40 chapters based on cutting-edge business and psychology research projects reveal what works and what doesn't work when we interact with each other. Each of the 40 chapters is a mini-masterclass in communicating better, explaining the research and showing you how to apply it for yourself to improve your own communication skills.Too often, conventional wisdom says one thing while research says another. Communication Genius cuts through the noise to bring you proven research and techniques for applying it that will simply make you a better all-round communicator.With chapters on body language, emotional intelligence, neuro-linguistic programming (NLP), presentations, mimicry, groupthink and the latest neuroscience, Communication Genius explodes some myths and gives you the best that science has to offer on communication. Quick to read and intensely practical, this book will bring a little communication genius into your day.'A must read if you want to communicate better' Professor Sir Cary Cooper, Manchester Business School, University of Manchester'Required reading for anyone seeking to better their communication skills in the workplace and otherwise' Dr Anastasia P. Rush, Clinical Psychologist, CEO HELLAS EAP (Greece)'Calls into question accepted 'beliefs' (Maslow's hierarchy) and introduces the reader to an array of new theories from "IQ" racism to the Obama effect' Kate Nowlan, Chief Executive, CiC Employee Assistance, Fellow Royal Society of Arts (FRSA)'Tony has done a fantastic job in pulling together an amazing number of articles and scientific studies and making them understandable to the lay person' Andrew Kinder, Chartered Counselling & Chartered Occupational Psychologist, Employee Assistance Professionals Association (EAPA -UK) Chair

Key Modern Architects provides an accessible and thought-provoking introduction to the work of the most significant architects of the modern era. Fifty short chapters introduce fifty key architects, from Le Corbusier to Aldo Van Eyck to Zaha Hadid, exploring their most influential buildings and developing a critique of each architect's work within a broader cultural and historical context. The selection represents the most influential architects working from 1890 to the present, those most likely to be taught on survey courses in modern architectural history, along with some lesser-known names with an equal claim to influence. Emphasis is placed on a critical and interpretative approach, allowing the student to position each architect in a cultural and intellectual context quickly and easily. Artistic, technical, social, and intellectual developments are brought to the fore - built and unbuilt projects, writings and influences. This approach brings to light the ideology behind architectural work, offering insights into each architect's working practice. - Helps students to develop a critical approach to understanding modern architectural history.- One chapter per architect - meaning chapters may be read individually as a concise resource for the study of an architect, or together as a coherent book-length history of the whole period of modern architecture. - Chapters are supported by boxed lists of each architect's most significant projects, along with suggestions for further reading as a springboard to further study and research. Combining the clarity and accessibility of a textbook with in-depth reading and a critical approach, Key Modern Architects provides an invaluable resource for both the classroom and for independent study in architectural and art history.

The fifth edition of Information Technology Law continues to be dedicated to a detailed analysis of and commentary on the latest developments within this burgeoning field of law. It provides an essential read for all those interested in the interface between law and technology and the effect of new technological developments on the law. The contents have been restructured and the reordering of the chapters provides a coherent flow to the subject matter. Criminal law issues are now dealt with in two separate chapters to enable a more focused approach to content crime. The new edition contains both a significant amount of incremental change as well as substantial new material and, where possible, case studies have been used to illustrate significant issues. In particular, new additions include:* Social media and the criminal law;* The impact of the decision in Google Spain and the `right to be forgotten';* The Schrems case and the demise of the Safe Harbour agreement;* The judicial reassessment of the proportionality of ICT surveillance powers within the UK and EU post the Madrid bombings;* The expansion of the ICANN gTLDs and the redesigned domain name registration and dispute resolution processes.

To fully function in today's global real estate industry, students and professionals need to understand how to implement essential and cutting edge quantitative techniques. This new book presents an easy-to-read guide to using quantitative analysis in real estate that will be accessible to advanced undergraduate and Masters students as well as meeting the requirements of modern professional practice. Through the use of numerous illustrative examples using data provided by major firms in the industry, the book provides an accessible introduction then builds up to more advanced quantitative analysis, modelling and forecasting of real estate markets. To help the reader in gaining a better understanding of the techniques, a number of real examples and case studies are included within the chapters. These examples are drawn either from the empirical real estate literature, or are specifically compiled and executed for this book. After reading this book, readers will be equipped to confidently carry out their own quantitative analysis and interpret conventional statistics encountered in similar studies in the fields of economics and finance. Both undergraduate and Masters level students, as well as real estate fund managers, private equity firms, investment banks, lenders and other entities will find this book to be essential reading.

Social workers work with people at all stages of life, tackling a multitude of personal, social, health, welfare, legal and educational issues. As a result, all social work students need to understand human growth and development throughout the lifespan.This fully revised and expanded second edition of this introductory text for social workers provides a knowledge base about human development from conception to death. It is designed to encourage understanding of a wide range of experiences: from the developmental trajectories of children in care, to adult mental distress and the experiences of people with dementia, to bereavement. Using engaging narratives to illustrate each topic, the authors clearly introduce and analyse different theoretical approaches, and link them to real-life situations faced by social workers.Packed with case studies, this student-friendly book includes overviews, summaries, questions and further reading in each chapter, as well as a `Taking it further' section providing greater depth on key theoretical issues. A reference section contains a glossary and overviews of the principal theories discussed throughout the book. It is an essential read for all social work students.

This exciting new book provides an overview of fifteen different contemporary social work practice settings, spanning across the statutory, voluntary, private and third sectors. It serves as the perfect introduction to the various roles social workers can have and the numerous places they can work, equipping students with the knowledge, skills and values required to work in areas ranging from mental health to fostering and adoption, and from alcohol and drug treatment services to youth offending. Each chapter provides:An overview of the setting, including the role of the social worker, how service users gain access to the service and key issues, definitions or terms specific to the settingLegislation and policy guidance related to the specific settingThe key theories and methods related to the settingBest practice approaches and the benefits and challenges of working within the settingCase examples illustrating the application of the information to practiceSocial work students will find this an invaluable handbook that they will refer to time and again throughout their education and into their assessed and supported year of employment.Contributors: Mark Baldwin, Jo Bell, Jenny Clifford, Jill Chonody, Clare Evans, Benedict Fell, Alinka Gearon, Issy Harvey, Caroline Hickman, Tony Jeffs, Debbie Martin, Malcolm Payne, Justin Rogers, Sue Taplin, Barbra Teater, John Watson, Michele Winter. "It is an excellent student introduction to this diverse profession. Full of information that provides a thought provoking read."Andrew Ellery, Social Care Professional "This book really is an excellent resource for social work students at an introductory level and for preparation for placement levels. It provides a comprehensive overview of a range of service user groups as well as specific issues such as domestic violence, homelessness and substance use. Each section is structured around the policy and legislative context and includes comment on theory, challenges and anti-oppressive practice with case examples to aid learning. The focus on the settings within which social work is practiced is particularly welcome and provides an essential companion to introductory books which look more at values, professional behaviour and skills. The range of different settings covered provides excellent preparation for students about to start a placement. The sections on rehabilitation of offenders and self-harm highlight topics that are often given less attention but may well be encountered by students on placement. I will certainly be including this book as essential reading for students on introductory and practice preparation modules."Allan Rose, Social Work Lecturer, Brunel University, UK

Understanding the fundamentals of conducting good science, that will have an impact, is the goal of every aspiring scientist. Providing a wealth of tips, How to be a Better Scientist is the book to read if you want to succeed in this competitive field. Helping readers gain an insight into what good science means and how to conduct it, this book is ideal to read cover-to-cover or dip into. It includes easily accessible guidance on topics such as: * What characteristics should a scientist have? * Understanding the hypothesis * Integrity in science * Lack of confidence and the embarrassment factor * Time management * Coping with rejection * Interacting with the science community With its broad focus, this friendly guide will enthuse, inspire and challenge, and is an essential companion for all aspiring scientists.

where Jeremy Richardson, Albert Weale and Hugh Ward were excellent hosts at the Department of Government and Thomas Christiansen a very good roommate. Having included the UK as a country where decision processes were far less participatory (and thus ‘worse’ in my own view) than those in the Netherlands, I started doing my first interviews there, which were mainly intended to identify suitable case studies for research. But then I read a highly critical review of a book that had a similar topic as my study. The critique was that cases of hazardous waste siting cannot adequately be studied without understanding their national context. This made me decide to devote some attention to the legal context of hazardous waste siting in the three countries of interest (which is of course only a part of the national context) and its development through the years. The study of the UK system of environmental regulation and land use planning was not a simple issue, and I was warned various times (for instance by Andrew Blowers at the Open University) that the legislation was highly complex and easily misinterpreted. I felt personally touched by such warnings and decided that I should perhaps approach the UK system a bit less as an evil empire and maybe be a bit more ‘objective’ in my appraisals.

How to Read Ethnography is an essential guide to approaching anthropological texts. It helps students to cultivate the skills they need to critically examine and understand how ethnographies are built up, as well as to think anthropologically and develop an anthropological imagination of their own. The authors reveal how ethnographically-informed anthropology plays a distinctive and valuable role in comprehending the complexity of the world we live in. This fully revised second edition includes fresh excerpts from key texts for analysis and comparison along with lucid explanations. In addition to concerns with argument, authority, and the relationship between theory and data, the book engages with the purpose, value, and accountability of ethnographic texts, as well as with their reception and usage. A brand new chapter looks at the kinds of collaboration between informants/consultants and anthropologists that go into the making of ethnographic writing.

Routledge English Language Introductions cover core areas of language study and are one-stop resources for students.Assuming no prior knowledge, books in the series offer an accessible overview of the subject, with activities, study questions, sample analyses, commentaries and key readings - all in the same volume. The innovative and flexible `two-dimensional' structure is built around four sections - introduction, development, exploration and extension - which offer self-contained stages for study. Each topic can also be read across these sections, enabling the reader to build gradually on the knowledge gained.Language and Power, Second Edition has been completely revised and updated and includes:a comprehensive survey of the ways in which language intersects and connects with the social, cultural and political aspects of power;an introduction to the history of the field, covering all the major approaches, theoretical concepts and methods of analysis in this important and developing area of academic study;coverage of all the `traditional' topics, such as race, gender and institutional power, but also newer topics such as the discourse of post-truth, and the power of social media;readings from works by seminal figures in the field, such as Robin Lakoff, Deborah Cameron and Teun van Dijk;real texts and examples throughout, including advertisements from cosmetics companies; newspaper articles and headlines; websites and internet media; and spoken dialogues such as political and presidential speeches;a supporting companion website that aims to challenge students at a more advanced level and which features extra reading, exercises, follow-up activities, and suggestions for further work.Language and Power will be essential reading for students studying English language or linguistics.

Boken er en dystopisk skildring av mennesker som er overlatt til sin egen skjebne. Etter den store katastrofen må far og sønn finne veien sørover i håp om at redningen kanskje er der ute et sted. Til fots langs veien i en utbrent post-apokalyptisk verden er ingenting sikkert, men de har hverandre. Romanen er filmatisert.

If you can recall the golden era of motorcycle sport then this is undoubtedly the book for you. Featuring sixteen scramblers and one and six days trials stars, this is a must read for all who lined the circuits on muddy Sundays and were glued to their TV sets on Winter afternoons. Author Andy Westlake is regarded as one of the UK's leading classic motorcycle journalists and this book is the perfect follow-up to his two previous books "Off Road Giants" volumes one and two. In this third volume Andy has once again managed to track down and interview some of the stars of this golden era in off road sport, including the former works Greeves rider and 250cc European champion Dave Bickers, ex works BSA star John Banks, and has even journeyed to Spain to interview Les Archer, the man who lifted the European 500cc crown on his works Norton in the mid 'fifties. A superbly written book brought alive by many excellent period photographs.

Curriculum and Assessment in English 3 to 11: A Better Plan provides an overview of the subject in considerable breadth and depth, and offers a clear, balanced and forceful critique of the current language and literacy curriculum and its assessment arrangements for 3- to 11-year-olds in England, and of developments in the area during the past thirty years. The book restates fundamental truths about how pupils speak, read and write English with confidence and control. It describes how English can be taught most effectively, calls for an urgent review of some aspects of the current National Curriculum and its associated tests, and - crucially - proposes viable alternatives. This invaluable resource for those working in English, language and literacy education has a wide perspective and takes a principled and informed pedagogical approach. Based on a series of much-admired booklets released by the UKLA in 2015, this accessible guide to both theory and practice will be of interest to teachers, student teachers, teacher-educators, advisers and policy-makers in the UK and internationally.

Curriculum and Assessment in English 11 to 19: A Better Plan provides an overview of the subject in considerable breadth and depth, and offers a clear, balanced and forceful critique of the current English curriculum and its associated examinations for 11- to 19-year-olds in England, and of developments in the area during the past thirty years.The book restates fundamental truths about how students speak, read and write English with confidence and control. It describes how English can be taught most effectively, calls for an urgent review of some aspects of the current National Curriculum and its examination arrangements, and - crucially - proposes viable alternatives. This invaluable resource for those working in English, media and drama education has a wide perspective and takes a principled and informed pedagogical approach.Based on a series of much-admired booklets released by the UKLA in 2015, this accessible guide to both theory and practice will be of interest to teachers, student teachers, teacher-educators, advisers and policy-makers in the UK and internationally.

t also presents the practical advice of those who have been there and done it and who now want to share their collective wisdom with you. The aim of which is to make education better, not just in your classroom but for everyone. A useful and inspirational book, it can be read straight through, or dipped in and out of for subject specific advice. A one-stop shop to inspire, invigorate and re-energise teachers and leaders alike, it's comprehensively written and covers an exceptional subject breadth. There is something for everyone, as it provides hints and ideas from both sides of the knowledge/skills debate, and challenges the perceived divide between primary and secondary pedagogy. Don't Change the Light Bulbs will provoke discussion, not only over its useful ideas, but also because of how it seeks to rethink the way we see imagined dichotomies in education. The wise words found within its pages will inspire your teaching, encouraging and supporting you, whilst you are stimulated to think outside of the classroom walls. For use by, and of interest to, everyone involved in the education sector. Contributors include: John Tomsett @Johntomsett @Chocotzar Sarah Findlater @Msfindlater Dan Williams @Furtheredagogy Stephen Lockyer @Mrlockyer Daniel Harvey @Danielharvey9 Ross Morrison McGill @Teachertoolkit Chris Deakin @Sociologyheaven Gwen Nelson @Gwenelope Mathew Pullen @Mat6453 Amy Harvey @Ms_Jamdangory Alex Quigley @Huntingenglish Phil Stock @Joeybagstock Steve Wheeler @Timbuckteeth Andrew Day @Andyphilipday Pete Jones @Pekabelo Dan Leighton @Danhleighton Amjad Ali @Astsupportaali Tom Sherrington @Headguruteacher Steph Ladbrooke @Learnbuzz Jill Berry @Jillberry102 Year 3 Pupil, Finley Julia Skinner @Theheads Office @Itsmotherswork Year 9 Pupil, Dylan @Book_Worm39 Alan O'Donohoe @Teknoteacher Dave Andress @Profdaveandress Mary Myatt @Marymyatt Emma Payne @Emma_Payneht Andy Lewis @Iteachre Chris Chivers @Chrischivers2 Jon Tait @Teamtait Amy Kennett @Amykennett Ian Gilbert @Thatiangilbert Martin Illingworth @Martinillingwor David Rogers @Daviderogers @H_Metal_Leader Jim Smith @Thelazyteacher Mark Anderson @Ictevangelist Ben Waldram @Mrwaldram Shaun Allison @Shaun_Allison Harry Fletcher-Wood @Hfletcherwood Tim Taylor @Imagineinquiry Iesha Small @Ieshasmall Hywel Roberts @Hywel_Roberts Rachel Orr @Rachelorr Martin Burrett @Ictmagic Kev Bartle @Kevbartle Thomas Starkey @Tstarkey1212 @Teachertweaks Jo Baker @Jobaker9 David Fawcett @Davidfawcett27 And Jenn Ludgate @Missjlud Jan Baker @Janbaker97 Sue Cowley @Sue_Cowley Andrew Old @Oldandrewuk Lisa Fernandez Adams @Lisafernandez78 @Cazzypot @Bergistra Rob Ward @Pgceng Lisa Jane Ashes @Lisajaneashes Nina Jackson @Musicmind Debra Kidd @Debrakidd Rachel Jones @Rlj1981 Chris Waugh @Edutronic_Net David Blow @Dtblow Amelia Stone @Revells7 Martyn Reah @Martynreah Stephen Logan @Stephen_Logan Scott Hayden @Bcotmedia Vic Goddard @Vicgoddard

MAIL ON SUNDAY BOOK OF THE YEAR OBSERVER BOOK OF THE WEEK'A compelling book' Evening Standard 'Essential' Sunday Times 'His soldier's dispatch is easy to read and vividly illustrates a sense of rising panic and embattlement. If you want to know what it was like to be there at the time, in the eye of a frenzied storm, then [Unleashing Demons] should be bought...' Andrew Marr, Sunday Times 'Vivid and immediate...It paints a brutally honest portrait of the British political class' Mail on Sunday 'A must-read account of history as it happened' Matt D'Ancona 'Jauntily written...naughty fun' Quentin Letts 'Unleashing Demons...has the vividness and pace of a political thriller. Extraordinarily candid...' Financial Times 'A fascinating book' Robert Elms, BBC 'The book that will set Westminster ablaze' Mail on Sunday 'Gripping reading' New Statesman 'Utterly fascinating...indispensable to appreciating this extraordinary phase in our history.' John Simpson 'The compelling insider's account' Nick Robinson 'This is one of the most vivid, frank and exciting inside accounts to have been written for years.' Anthony Seldon 'A gripping fly-on-the-wall account.' Robert Peston As David Cameron's director of Politics and communications, Craig Oliver was in the room at every key moment during the EU referendum - the biggest political event in the UK since World War 2. Craig Oliver worked with all the players, including David Cameron, George Osbourne, Barack Obama, Angela Merkel, Jeremy Corbyn, Boris Johnson, Michael Gove, Theresa May and Peter Mandelson. Unleashing Demons is based on his extensive notes, detailing everything from the decision to call a referendum, to the subsequent civil war in the Conservative Party and the aftermath of the shocking result. This is raw history at its very best, packed with enthralling detail and colourful anecdotes from behind the closed doors of the campaign that changed British history.

Phill Savidge is widely credited as being the main instigator of the Britpop music movement that swept the UK in the mid-1990s. Savidge was co-founder and head of legendary public relations company Savage and Best, the company that represented most of the artists associated with the scene, including Suede, Pulp, The Verve, Elastica, Kula Shaker, Spiritualized, Menswear, The Auteurs, and Black Box Recorder. Phill suggests that Britpop came about by accident because he refused to represent any American bands. He subsequently ended up with an extremely accessible, media-friendly roster that `lived round the corner and included the most exciting press-worthy acts of the era. His unique experience at the epicentre of Britpop led to many intimate, not entirely self-congratulatory encounters with a who s who of popular culture including Brett Anderson, Damon Albarn, Roy Orbison, David Bowie, Joe Strummer, Lou Reed, Michael Barrymore, Richard Ashcroft, Andrew Lloyd Webber, Mick Jagger, George Lucas, Damien Hirst, and Dave Stewart, among others. But did he really Sellotape a cassette of Suede s `Animal Nitrate single to a purple velvet cushion with a note that said `another great disappointment and then bike it to the NME? And could he and Jarvis Cocker really have fallen out simply because a journalist thought he was more glamorous than the Pulp front man? If you ve ever wondered what it s like to represent Hirst, Cocker, and The Verve in the same decade, and then wake up in bed with Keith Allen in the Ritz in Paris courtesy of Mohammed Al Fayed then you should read this book. Imagine David Sedaris with a hangover and an expense account and you re halfway to appreciating the delinquent delights of Lunch With The Wild Frontiers.

THE SUNDAY TIMES BESTSELLER 'Confused about the EU referendum? In the dark about which way to vote? Daniel Hannan's invaluable vade mecum will illuminate the whole question, showing why voting to leave is a leap back into the light' Boris Johnson. 'Powerful, intelligent, hard-hitting, well-written ... absolutely required reading for every Briton who is considering voting on 23 June' Andrew Roberts. MEP and award-winning political writer Daniel Hannan argues for a British exit ahead of the coming referendum. Hannan demonstrates that the EU is past its sell-by date, rendered obsolete by technological advances, shrinking economically and less relevant to our economic needs than ever. Worse than that, he shows that the EU can't reform, can't be democratic and can't be divorced from its goal of ever-closer political union. Staying in does not mean staying the same and a vote to leave - far from being the risky choice - is actually the safe one. Finally, Hannan argues that Britain doesn't have to stay in the EU to remain at the heart of Europe and considers the global role a confident nation freed from EU strictures could play. 'Before voting in this historic referendum you should read this brilliant book. If you've decided to vote Leave this will enthuse you, if you're not yet sure, it will convince you' Michael Gove. 'A 'must read' for anyone who is surprised that so many of us now want to leave the EU' Lord Owen. 'I defy anyone who is undecided on the EU to read this book and not be a convinced Leaver. The case against EU membership is not Left-wing or Right-wing: it's democratic. Daniel Hannan shows how bright the UK's future will be once we leave behind the corporatist racket in Brussels' Kate Hoey. 'I defy anyone who is undecided on the EU to read this book and not be a convinced Leaver' Kate Hoey. 'The perfect book for someone who wants to hear a calm, clear set of reasons for leaving the EU' Baroness Jones.'When it comes to the EU Dan Hannan has forgotten more than most people ever knew. He knows it from the inside, deep inside. He knows the venality, the incompetence, the bloated budgets and salaries, the many failures cynically covered up. He knows the staggering sums dragged from the pockets of the British taxpayer and the miserable return we get from them. The Brussels-worshipping brigade would be very wise not even to try to contest the points he makes in this book. For the rest of us it's an eye-opener.' Frederick Forsyth. 'The case against the EU should be made in positive, optimistic and internationalist terms. Daniel Hannan has done us a favour by making the democratic and economic case for independence. If you're undecided, this book might surprise you' Helena Morrissey.